Efficacy and safety of rib-guided percutaneous thoracic sympathetic radiofrequency thermocoagulation at two different targets for primary palmar hyperhidrosis: a randomized controlled trial.
Yue Wu, Qianqian Xing, Hua Huang et al.
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In 30 seconds
This randomized controlled trial evaluated the efficacy and safety of computed tomography-guided percutaneous thoracic sympathetic radiofrequency thermocoagulation (RFT) for severe primary palmar hyperhidrosis, comparing targets at the upper versus lateral margin of the fourth rib head. The study found that targeting the lateral margin resulted in significantly lower Hyperhidrosis Disease Severity Scale (HDSS) grades and Dermatology Life Quality Index (DLQI) scores at 6 and 12 months.
Key findings
- Group L showed significantly lower HDSS grades at 6 and 12 months compared to Group U.
- Group L had lower DLQI scores at 6 and 12 months than Group U.
- Patient satisfaction was significantly higher in Group L at 12 months (p = 0.036).
- Immediately post-RFT, finger perfusion index was significantly higher in Group L than in Group U.
Why it matters
Understanding the optimal target for RFT in treating primary palmar hyperhidrosis can enhance patient outcomes, improve quality of life, and increase satisfaction with the procedure, which is crucial for effective management of this condition.