Primary ovarian non-small cell neuroendocrine carcinoma in an adolescent: The youngest case reported to date.

Pathol Res PractAug 25, 2026 (epub)

Shuhong Zhang, Qingwei Liu, Jiankui Li

✦ AI-curated · Sources linked

Case in brief

A 15-year-old girl presented with acute abdominal pain and a large cystic-solid abdominopelvic mass. Emergency fertility-sparing cytoreductive surgery confirmed the diagnosis of primary ovarian non-small cell neuroendocrine carcinoma (NSCNEC) through histopathology and immunohistochemistry. The patient received chemotherapy and remained recurrence-free at 6 months, highlighting the need for awareness of this rare tumor in adolescents.

Diagnostic / clinical pearl

Clinicians should consider primary ovarian non-small cell neuroendocrine carcinoma in adolescent patients presenting with abdominal pain and an abdominopelvic mass, despite its rarity.

Why it matters

This case underscores the importance of recognizing rare tumors in younger populations and supports the need for a global registry and standardized management for such cases.

Source

Published in Pathol Res Pract. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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