Acute water ingestion influences lean soft tissue estimation from dual-energy x-ray absorptiometry: Implications for clinical diagnosis.

Clin Nutr ESPENAug 29, 2026 (epub)

Tina E Sergi, Brandon M Roberts, Grant M Tinsley et al.

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In 30 seconds

This randomized controlled trial investigated the effects of acute water ingestion (AWI) on dual-energy X-ray absorptiometry (DXA) estimates of lean soft tissue (LST) in 46 participants. Results showed that 1000 mL of AWI significantly increased whole-body LST compared to lower volumes and control, with trunk LST accounting for most of the change. The study highlights the need for standardized protocols regarding water intake before DXA scans.

Key findings

  • 1000 mL of AWI significantly increased whole-body LST compared to control and lower volumes.
  • The 500 mL AWI group showed significantly higher LST at 90 minutes compared to control and 250 mL groups.
  • Trunk LST changes accounted for 53%-99% of the increase in whole-body LST.
  • AWI had no significant effect on appendicular lean soft tissue.

Why it matters

Understanding the impact of acute water ingestion on DXA measurements is crucial for accurate diagnosis of conditions like sarcopenia. Clinicians must be aware of these confounding factors to ensure reliable assessments.

Source

Published in Clin Nutr ESPEN. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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