Glycemic and safety outcomes of the insulin-only bionic pancreas in older adults and individuals with impaired awareness of Hypoglycemia: a post hoc analysis of a randomized pivotal trial.

Diabetes Res Clin PractAug 30, 2026 (epub)
Clinical ResearchEndocrinologyGeriatrics

Puguh Oktavian, Citrawati Dyah Kencono Wungu, Indah Mohd Amin et al.

✦ AI-curated · Sources linked

In 30 seconds

This post hoc analysis of a randomized controlled trial evaluated the efficacy and safety of the iLet Bionic Pancreas in 96 older adults and individuals with impaired awareness of hypoglycemia. The study found that time-in-range significantly increased by 7.49% with BP-Asp/Lis and by 8.28% with BP-Fiasp compared to standard care, indicating improved glycemic control.

Key findings

  • Time-in-range increased by 7.49% with BP-Asp/Lis compared to standard care.
  • Time-in-range increased by 8.28% with BP-Fiasp compared to standard care.
  • Severe hypoglycemia occurred in four participants on BP-Asp/Lis and one on standard care.

Why it matters

Improved glycemic control in older adults and those with impaired awareness of hypoglycemia is crucial, as these populations are at higher risk for severe hypoglycemic events. The Bionic Pancreas may offer a safer alternative for managing diabetes in these vulnerable groups.

Source

PubMed · PMID 42669381

Published in Diabetes Res Clin Pract. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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