Severe amnestic-cognitive syndrome after right-sided resection in a patient with bilateral trigonal choroid plexus xanthogranulomas: illustrative case.
Amir M Poreh, Lior Ungar, Shachar Zion Shemesh et al.
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Case in brief
A 63-year-old man with bilateral trigonal choroid plexus xanthogranulomas presented with headaches and memory complaints. Following resection of the right-sided lesion, he developed a severe amnestic-cognitive syndrome characterized by an inability to retain new information and significant memory disturbances. Neuropsychological evaluation three months later revealed severe impairments in verbal learning and retrograde memory.
What made this case unusual
The case highlights the unexpected severe cognitive decline following surgery for a typically asymptomatic lesion, emphasizing the potential risks to memory networks associated with bilateral trigonal xanthogranulomas.
Diagnostic / clinical pearl
Clinicians should consider the cognitive risks associated with surgical intervention for bilateral trigonal choroid plexus xanthogranulomas, particularly regarding memory network integrity.
Why it matters
This case underscores the importance of preoperative cognitive assessment and structured postoperative follow-up to better understand the neuropsychological impacts of surgical treatment for intraventricular lesions.