SAGES clinical practice guidelines for the management of symptomatic walled-off pancreatic necrosis.
Elisa C Calabrese, Dena Shehata, Bethany J Slater et al.
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In 30 seconds
This systematic review developed clinical practice guidelines for managing symptomatic walled-off pancreatic necrosis (WOPN) in adults. The guidelines, based on very low certainty of evidence, include conditional recommendations favoring endoscopic management over image-guided intervention and minimally invasive surgery over open surgery. The findings emphasize the need for further research to strengthen the evidence base.
Key findings
- Conditional recommendation for endoscopic management versus image-guided intervention.
- Conditional recommendation for image-guided intervention versus open surgery.
- Conditional recommendation for minimally invasive surgery versus endoscopic intervention.
- Conditional recommendation for a pure endoscopic approach versus a step-up approach.
Why it matters
These guidelines address a significant complication of acute pancreatitis, providing clinicians with evidence-based recommendations to improve patient outcomes in managing WOPN, despite the low certainty of the evidence.
What to keep in mind
All recommendations were based on very low certainty of evidence.