Tailoring Resistance Exercise for Knee Osteoarthritis: An Intervention Systematic Review With Dose-Response Meta-analysis of the Effects of Intensity and Volume.
Rodrigo Núñez-Cortés, Luis Suso-Martí, Andrea Tur-Boned et al.
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In 30 seconds
This systematic review and dose-response meta-analysis evaluated the effects of isotonic resistance exercise on pain, function, and strength in 791 individuals with knee osteoarthritis. The findings suggest that isotonic resistance training may reduce pain and improve function and muscle strength, with the most significant benefits observed at specific exercise volumes and intensities. Notably, 6000 repetitions were associated with a mean pain reduction of -3.52.
Key findings
- Isotonic resistance training may reduce pain, improve function, and increase muscle strength in knee OA patients.
- Very light- to moderate-intensity exercise produced the greatest reductions in pain.
- Peak functional improvements were noted at 2600 repetitions of moderate intensity (MD, -16.66).
- Maximal strength gains were observed at 1600 repetitions (standardized MD, 0.12).
Why it matters
Understanding the optimal intensity and volume of resistance exercise can help clinicians design effective rehabilitation programs for patients with knee osteoarthritis, potentially enhancing patient outcomes in pain management and functional ability.