A 12-week, double-blind, quasi-randomized, placebo-controlled study to evaluate the efficacy and safety of Coleus forskohlii (Forcslim) on body weight loss.
Sadashiva Channangihalli Thimmegowda, Firoz Hirehal Hussain Mirza, Rajesh Venkataraman et al.
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In 30 seconds
This 12-week, double-blind, quasi-randomized, placebo-controlled trial evaluated the efficacy and safety of Coleus forskohlii (Forcslim) in 60 overweight individuals aged 20-70. The Forcslim group experienced significant reductions in body weight (-1.93 kg) and waist circumference (-1.83 cm) compared to placebo, alongside improvements in lipid profiles.
Key findings
- Forcslim group showed a body weight reduction of -1.93 kg compared to placebo (p < 0.001).
- Waist circumference decreased by -1.83 cm in the Forcslim group (p < 0.01).
- Triglyceride levels were significantly reduced in the Forcslim group (p < 0.01).
- High-density lipoprotein levels increased significantly in the Forcslim group (p = 0.001).
Why it matters
The rising prevalence of obesity necessitates effective interventions. This study suggests that Coleus forskohlii extract may provide a natural alternative for weight management, potentially reducing reliance on synthetic medications.