DOTATATE-PET in custom spheno-orbital implant design for meningiomas with orbital involvement: a case series.
Joshua M Tennyson, Rishi Jain, Chris Z Wei et al.
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Case in brief
This case series involved four patients with hyperostosing spheno-orbital meningiomas who underwent cranio-orbital resection followed by reconstruction using custom polyetheretherketone implants. DOTATATE-PET imaging was utilized to assess tumor infiltration beyond what was visible on CT and MRI, guiding surgical planning. Postoperatively, visual outcomes stabilized or improved, and the exophthalmos index showed improvement in all patients, with three returning to normal globe position.
Diagnostic / clinical pearl
DOTATATE-PET imaging can significantly enhance the detection of meningioma infiltration into bone, which is often underestimated by standard imaging techniques.
Why it matters
The integration of molecular imaging with custom implant design represents a promising approach for managing complex cases of meningiomas with orbital involvement, potentially improving surgical outcomes.