The Effect of Exercise on Reproductive and Metabolic Outcomes in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.
Kangxi Zou, Yunlu Ping, Qiuyang Wei et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the effects of exercise on reproductive and metabolic outcomes in 1044 women with polycystic ovary syndrome (PCOS) across 22 randomized controlled trials. The findings revealed that exercise significantly reduced total testosterone, free testosterone, fasting insulin, and HOMA-IR, while increasing high-density lipoprotein levels, with more pronounced effects observed in those engaging in at least 150 minutes of exercise per week.
Key findings
- Exercise significantly reduced total testosterone levels in women with PCOS.
- Fasting insulin levels decreased significantly with exercise intervention.
- Moderate-to-low intensity exercise increased sex hormone-binding globulin.
- Non-obese women with PCOS experienced greater reductions in total testosterone compared to obese women.
Why it matters
Understanding the impact of exercise on PCOS can guide clinicians in recommending lifestyle interventions that improve reproductive and metabolic health. Tailoring exercise regimens based on individual characteristics may enhance treatment efficacy.