Continuous Renal Replacement Therapy for Cytokine Storm in Diabetic Kawasaki Shock Syndrome.
Zhijiang Zhou, Ping Ling, Rong Tang et al.
✦ AI-curated · Sources linked
Case in brief
A 3-year, 10-month-old boy with poorly controlled type 1 diabetes and autoimmune thyroiditis presented with Kawasaki disease shock syndrome and diabetic ketoacidosis. After failing to respond to intravenous immunoglobulin and high-dose aspirin, he experienced refractory shock and metabolic acidosis. Initiation of continuous venovenous hemodiafiltration resulted in rapid hemodynamic stabilization and resolution of hyperinflammation.
Diagnostic / clinical pearl
Continuous renal replacement therapy can be an effective rescue intervention in critically ill pediatric patients experiencing cytokine storm and metabolic crisis when standard treatments are ineffective.