Systemic amyloidosis diagnosed by labial salivary gland biopsy.

BMJ Case RepSep 1, 2026 (epub)
Case ReportHematologyInternal Medicine (General)

Fiona Lam Guan, Conor O'Gorman, Simon Rajendran et al.

✦ AI-curated · Sources linked

Case in brief

A man in his 60s presented with acute decompensating heart failure and was initially evaluated for cardiac amyloidosis. Due to difficulties in obtaining a tissue sample, he was referred for a labial salivary gland biopsy, which revealed amyloid deposits. This led to a confirmed diagnosis of amyloid light-chain amyloidosis, highlighting the utility of this biopsy method.

Diagnostic / clinical pearl

Labial salivary gland biopsy is a minimally invasive and effective diagnostic tool for systemic amyloidosis, particularly when other tissue sampling methods are challenging.

Source

PubMed · PMID 42680503

Published in BMJ Case Rep. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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