Unique Thyroid Carcinoma With Somatic Inactivating TSC2 Mutations, Follicular and Melanocytic Differentiation and Distinct Morphologic Features.

Am J Surg PatholSep 2, 2026 (epub)
Case ReportPathology (Anatomic & Clinical)Medical GeneticsOpen access

Chatchanan Ausavarungnirun, Muhammad Usama, Daniel Ngov et al.

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Condensed from the publisher's abstract. An xxcode editorial summary of this publication has not been generated yet.

From the abstract

Thyroid carcinomas with mutations in the TSC2 gene have been described rarely. Here, we report a unique thyroid carcinoma that has somatic mutations in TSC2 , follicular and melanocytic differentiation and distinct morphologic features, supported by a comprehensive molecular-genetic analyses. No other known pathogenic driver mutations were identified.

Source

PubMed · PMID 42682160Free full text on PubMed Central

Published in Am J Surg Pathol. The text above is extracted from the publisher's own abstract and has not been edited by xxcode. For clinical decisions, review the original publication.

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