Comparison of a 755-nm picosecond laser and a 1565-nm nonablative fractional laser for the treatment of atrophic acne scars: a 20-week prospective, randomized, split-face clinical study.
Lasers Med SciSep 2, 2026 (epub)
Junfeng Qi, Xinying Li, Xia Shu et al.
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial compared the efficacy and safety of a 755-nm picosecond laser (P-DLA) and a 1565-nm nonablative fractional laser (NAFL) in 27 patients with atrophic acne scars. Both treatments significantly improved scar appearance, but P-DLA resulted in higher patient satisfaction (P = 0.035) and a better safety profile, including shorter erythema and edema durations.
Key findings
- Both P-DLA and NAFL showed significant improvements in scar appearance (P < 0.001).
- No statistically significant differences in efficacy were observed between P-DLA and NAFL.
- P-DLA resulted in higher patient satisfaction compared to NAFL (P = 0.035).
- P-DLA had a more favorable safety profile, with shorter durations of erythema and edema.
Why it matters
Understanding the comparative effectiveness and safety of different laser treatments for atrophic acne scars can guide clinicians in selecting appropriate therapies, ultimately improving patient outcomes and satisfaction.