Skin barrier repairing and anti-aging effects evaluation of a comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol after PicoWay laser: a randomized controlled study.
Lasers Med SciSep 3, 2026 (epub)
Huijuan Liu, Baiyu Li, Xiaofeng He et al.
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In 30 seconds
This randomized controlled trial evaluated the effects of a comprehensive topical regimen with niacinamide, Pro-Xylane, and panthenol on skin barrier repair and anti-aging in 88 Chinese females post-PicoWay laser treatment. The test group showed lower transepidermal water loss and higher hydration after 14 days, alongside significant improvements in skin elasticity, firmness, and reduced wrinkles after 112 days compared to the control group.
Key findings
- Test group had lower transepidermal water loss and higher hydration after 14 days compared to control.
- After 112 days, the test group showed increased skin elasticity and firmness.
- The test group experienced a significant reduction in wrinkles and improved skin tone and texture.
- Dermatologists reported excellent tolerability with minimal adverse events.
Why it matters
The findings suggest that a targeted topical regimen can enhance skin recovery and anti-aging effects following laser treatments, potentially improving patient outcomes in dermatological practice.