When Crystalloids Tell the Story: Amylase Crystalloids in Salivary Gland Cytology.

CytopathologySep 3, 2026 (epub)
Case ReportPathology (Anatomic & Clinical)

Pallavi Saraf, Vaibhav Saini, Shubham Kabra et al.

✦ AI-curated · Sources linked

Case in brief

A 59-year-old female presented with a parotid swelling. Ultrasonography identified a cystic lesion, and fine needle aspiration yielded yellowish fluid. Cytology revealed numerous nonbirefringent rectangular to rhomboidal crystalloids consistent with amylase crystalloids, amidst a mixed inflammatory background. The diagnosis was chronic sialadenitis with amylase crystalloids, which resolved after aspiration without recurrence.

Diagnostic / clinical pearl

The presence of amylase crystalloids in salivary gland cytology can indicate benign conditions, aiding in the differentiation of neoplastic from non-neoplastic lesions.

Source

PubMed · PMID 42687848

Published in Cytopathology. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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