The effect of BIS-guided sevoflurane anesthesia on postoperative nausea and vomiting in pediatric adenoidectomy: a prospective randomized controlled trial.
Sao Paulo Med JAug 31, 2026 (epub)
Engin Cetin, Ayse Sencan, Ahmet Yuksek et al.
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In 30 seconds
This prospective randomized controlled trial evaluated the impact of BIS-guided sevoflurane anesthesia on postoperative nausea and vomiting (PONV) in 58 children aged 3-8 undergoing adenoidectomy. The study found that PONV occurred less frequently in the BIS-guided group compared to standard care, with an odds ratio of 0.212 (95% CI: 0.067-0.675; p = 0.009).
Key findings
- PONV within 24 hours was significantly lower in the BIS-guided group (p = 0.015).
- BIS-guided anesthesia was associated with lower odds of PONV (OR = 0.212; 95% CI: 0.067-0.675; p = 0.009).
- Sevoflurane consumption was reduced in the BIS-guided group (p < 0.05).
- Emergence time was shorter in the BIS-guided group (p < 0.05).
Why it matters
Reducing postoperative nausea and vomiting in pediatric patients can enhance recovery and improve overall patient satisfaction. This study suggests that BIS monitoring may be an effective strategy to optimize anesthetic management in this population.