Value of shear wave elastography in evaluating response to neoadjuvant chemotherapy in breast cancer: A systematic review and meta-analysis.

J Int Med ResSep 3, 2026 (epub)
Clinical ResearchOncology (Medical)Radiology (Diagnostic)

Bin Lian, Chuanxin Ye, Fengjie Li et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and meta-analysis evaluated the effectiveness of shear wave elastography in assessing the pathological response to neoadjuvant chemotherapy in breast cancer patients. Analyzing data from 15 trials involving 1402 patients, the study found a pooled sensitivity of 0.68 and specificity of 0.73, indicating moderate diagnostic performance with an area under the curve of 0.85.

Key findings

  • Pooled sensitivity of shear wave elastography was 0.68 (95% CI: 0.49-0.86).
  • Pooled specificity was 0.73 (95% CI: 0.60-0.87).
  • The pooled diagnostic odds ratio was 13.06 (95% CI: 8.42-20.25).
  • The area under the curve for diagnostic performance was 0.85 (95% CI: 0.82-0.88).

Why it matters

Understanding the diagnostic performance of shear wave elastography can aid clinicians in monitoring treatment responses in breast cancer, potentially improving patient management and outcomes during neoadjuvant chemotherapy.

Source

PubMed · PMID 42690897

Published in J Int Med Res. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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