Transverse Tibial Transport for Limb Salvage in Ischemic Lower Extremity Disease: Technique, Mechanisms, and Clinical Outcomes-A Systematic Review.
Orthop Clin North AmJul 17, 2026 (epub)
Samuel Raszka, Max Michalski, Charles Moon
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In 30 seconds
This systematic review examines transverse tibial transport (TTT) for limb salvage in patients with ischemic lower extremity disease. The technique enhances angiogenesis and microcirculatory regeneration without altering macrovascular structures. Notably, TTT combined with endovascular therapy improves amputation-free survival compared to endovascular therapy alone.
Key findings
- TTT stimulates angiogenesis and microcirculatory regeneration in ischemic limbs.
- Combined TTT plus endovascular therapy improves amputation-free survival versus endovascular therapy alone.
- The technique utilizes an external fixator to distract the proximal tibial cortical bone.
Why it matters
Understanding TTT's mechanisms and outcomes can inform clinicians about innovative surgical options for patients with ischemic lower extremity disease, potentially improving limb salvage rates.