Comparative efficacy of various wound dressings on scar formation following thyroidectomy: a systematic review and meta-analysis.

J Comp Eff ResSep 4, 2026 (epub)

Yixue Jiang

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In 30 seconds

This systematic review and meta-analysis evaluated the effectiveness of various postoperative wound interventions on scar formation following thyroidectomy in adults. The analysis included 14 randomized controlled trials, revealing that while overall interventions did not significantly improve scar outcomes (SMD: -0.21; 95% CI: -0.45 to 0.04; p = 0.10), wound-protector devices showed a significant improvement (SMD: -0.84; p < 0.001).

Key findings

  • Overall, postoperative wound interventions did not significantly improve scar outcomes (SMD: -0.21; p = 0.10).
  • Wound-protector devices demonstrated a significant improvement in scar outcomes (SMD: -0.84; p < 0.001).
  • Tissue adhesives showed no measurable scar-quality advantage over conventional sutures (SMD: 0.14; p = 0.29).
  • Evidence for continuous diffusion oxygen therapy remains preliminary, evaluated in only one trial.

Why it matters

Understanding the comparative effectiveness of wound interventions is crucial for clinicians aiming to minimize scarring and enhance cosmetic outcomes after thyroid surgery. This knowledge can guide postoperative care strategies.

Source

Published in J Comp Eff Res. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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