Systemic Corticosteroids in the Perioperative Setting for Prevention of Pyoderma Gangrenosum During Reconstructive Surgery.

J Drugs DermatolSep 1, 2026

Lindsay Skylar Li, William C Lau, Mark Lebwohl

✦ AI-curated · Sources linked

Case in brief

A patient developed pyoderma gangrenosum (PG) following multiple breast augmentation surgeries. This case highlights the successful use of a combination of cyclosporine and prednisone to prevent PG recurrence during subsequent breast reconstruction. The treatment was administered both preoperatively and postoperatively, demonstrating effective management of this condition in a surgical context.

Diagnostic / clinical pearl

Clinicians should consider the risk of pyoderma gangrenosum in patients with a history of surgical procedures, particularly in the context of breast augmentation, and may benefit from prophylactic corticosteroid therapy.

Source

Published in J Drugs Dermatol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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