A Novel Moisturizer Formulated With Micronized Centella asiatica and Mandelic Acid Improves Mature, Crepey Skin.
J Drugs DermatolSep 1, 2026
Clinical ResearchDermatology
Glynis Ablon, Christine Emesiani, Sindhu Garimella et al.
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial evaluated the efficacy and safety of a novel moisturizer, GC cream, in 40 to 60-year-old subjects with mature, fragile skin. Over 12 weeks, significant improvements were observed in skin crepiness, photodamage, and firmness, alongside decreased skin pH and enhanced hydration. No adverse events were reported.
Key findings
- GC cream significantly improved skin crepiness and photodamage after 12 weeks.
- Skin pH decreased, indicating improved skin condition.
- Subjects reported high satisfaction with the GC cream's effects.
- No adverse events were reported during the study.
Why it matters
The findings highlight the potential of targeted moisturizers in improving skin quality for aging patients, addressing common issues such as crepiness and dryness. This can enhance patient satisfaction and overall skin health.