CytoSorb Application for Successful Control of Life-Threatening Gastrointestinal Bleeding Following Rivaroxaban Administration.
Liliya Raeva, Miroslav Petrov, Mihail Cholakov et al.
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Case in brief
A 68-year-old man with a history of colonic diverticular disease experienced severe lower gastrointestinal bleeding while on rivaroxaban. Standard resuscitative and endoscopic interventions failed, and emergency surgery was too risky. Due to the unavailability of the specific reversal agent, CytoSorb hemoperfusion combined with continuous renal replacement therapy was initiated, leading to rapid hemodynamic stabilization and cessation of bleeding, thus avoiding surgery.
Diagnostic / clinical pearl
Extracorporeal hemoperfusion may be a viable alternative for managing life-threatening bleeding in patients on direct oral anticoagulants when standard reversal agents are unavailable.