Substance use and co-occurring mental health conditions among adolescents and young adults in North America: a systematic review.

BMC PsychiatrySep 3, 2026 (epub)
Clinical ResearchPsychiatryOpen access

Gemy Kuriakose, Jenny Seo, Negar Asgharipourzahmati et al.

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In 30 seconds

This systematic review examined the prevalence and associated factors of substance use and co-occurring mental health conditions among adolescents and young adults in North America. It analyzed 29 studies, revealing that depressive, anxiety-related, and trauma-related issues frequently co-occur with substance use. The findings underscore the need for integrated care approaches tailored to this population.

Key findings

  • Depressive, anxiety-related, and trauma-related mental health issues were commonly reported alongside substance use.
  • Trauma exposure and adverse childhood experiences were frequently associated with substance-related problems.
  • Care-related implications were largely suggested as future directions rather than evaluated service models.

Why it matters

Understanding the prevalence and interplay of substance use and mental health conditions in young populations is crucial for developing effective interventions. Clinicians can better address these co-occurring issues by recognizing the importance of integrated and trauma-informed care.

Source

Published in BMC Psychiatry. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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