Combined effects of strength training, whey protein, and HMB on sarcopenia in older people: A systematic review and meta-analysis.
Jordan Hernandez-Martinez, Izham Cid-Calfucura, Edgar Vásquez-Carrasco et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the effects of strength training combined with whey protein and HMB supplementation on sarcopenia in older adults. Analyzing 7 randomized controlled trials with 472 participants, the study found significant increases in fat-free mass and physical performance metrics, including maximal isometric handgrip strength (effect size = 1.38).
Key findings
- Significant increase in fat-free mass (effect size = 0.39) was observed.
- Maximal isometric handgrip strength improved significantly (effect size = 1.38).
- Chair stand test and 6-minute walk test both showed significant improvements (effect size = 0.33).
- Whey protein combined with strength training led to a significant increase in maximal isometric handgrip strength (effect size = 0.49).
Why it matters
Understanding the combined effects of strength training and supplementation can help clinicians develop effective interventions for older patients with sarcopenia, potentially improving their physical performance and quality of life.
What to keep in mind
The study is limited by a small number of RCTs and moderate-to-high risk of bias in the included studies.