Cardiorespiratory fitness in people with bipolar disorder: A systematic review and meta-analysis.
Vitória Joana Paes Arida, Lucas Melo Neves, Tabatah Hellen Santos Gomes et al.
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In 30 seconds
This systematic review and meta-analysis evaluated cardiorespiratory fitness (CRF) in individuals with bipolar disorder (BD) compared to controls. The analysis included 20 studies, revealing that adults with BD had a mean CRF of 27.0 mL·kg -1 ·min -1, which is 7.4 mL·kg -1 ·min -1 lower than controls (p = 0.006).
Key findings
- Mean CRF in adults with BD was 27.0 mL·kg -1 ·min -1.
- CRF was 7.4 mL·kg -1 ·min -1 lower in BD than in controls (p = 0.006).
- The analysis included 20 studies, with significant heterogeneity observed.
- No conclusions about the efficacy of physical activity interventions on CRF could be drawn.
Why it matters
Understanding CRF levels in patients with bipolar disorder is crucial, as reduced fitness can increase the risk of cardiovascular issues and mortality. This highlights the need for targeted interventions to improve physical health in this population.
What to keep in mind
The evidence base is small, cross-sectional, and heterogeneous, limiting the robustness of findings.