Delusional infestation in Parkinson disease: a case report of medication-induced psychosis.
Ali Zare Dehnavi, Jorge Patino, Kendra M Anderson et al.
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Case in brief
A 66-year-old woman with Parkinson disease developed visual and tactile delusions of a parasitic infestation while on dopaminergic therapy. Neuropsychological testing indicated largely preserved cognitive function, with mild weaknesses in processing speed and problem-solving. Her symptoms resolved after discontinuing amantadine, suggesting an iatrogenic cause linked to her medication.
Diagnostic / clinical pearl
Delusional infestation can occur in patients with Parkinson disease receiving dopaminergic medications, and may be reversible upon adjusting treatment.
Why it matters
This case emphasizes the need for neuropsychological assessment in patients with Parkinson disease experiencing psychosis, as it can aid in identifying medication-induced symptoms.