Multimodal Management of Advanced Metastatic Prostate Cancer: Excellent Response Following Resection of Brain Metastasis and 177Lu-PSMA Therapy.

Clin Nucl MedAug 4, 2026 (epub)
Case ReportOncology (Medical)Neurosurgery

Ghasemali Divband, Hamidreza Amini, Hamid Saeidi Saedi et al.

✦ AI-curated · Sources linked

Case in brief

A 68-year-old man with metastatic prostate adenocarcinoma underwent various treatments, including androgen-deprivation therapy and chemotherapy. After detecting a PSMA-avid brain lesion via 68Ga-PSMA PET/CT, he received brain radiotherapy. Following progression of the brain lesion and skeletal metastases, he had the lesion surgically resected and completed 4 cycles of 177Lu-PSMA-617, resulting in near-complete resolution of skeletal metastasis.

Diagnostic / clinical pearl

This case underscores the effectiveness of multimodal management, particularly the role of 177Lu-PSMA therapy, in treating brain metastases from prostate cancer.

Source

PubMed · PMID 42710083

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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