Effect of Bariatric Surgery on Improvement of Retinal Microvasculature in Patients With Obesity: A Systematic Review and Meta-Analysis.
Syifa Salsabila, Wilbert Huang, Aklila Qurrota A'ini Sumardi et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review and meta-analysis evaluated the impact of bariatric surgery on retinal microvasculature in 283 patients with obesity. The study found that bariatric surgery significantly increased the central retinal arteriolar equivalent (CRAE) by 4.02 μm and decreased the central retinal venular equivalent (CRVE) by 6.75 μm, while the arteriovenous ratio (AVR) increased by 0.03. Sensitivity analyses confirmed the robustness of these findings.
Key findings
- Bariatric surgery increased CRAE by 4.02 μm (CI [0.26-7.78], p = 0.04).
- CRVE decreased significantly by 6.75 μm (CI [-7.42 to -6.07], p < 0.01).
- AVR increased significantly by 0.03 (CI [0.02-0.05], p < 0.01).
- Sensitivity analysis showed a stronger CRAE effect of +5.41 μm (CI [4.59-6.22], p < 0.01).
Why it matters
Understanding the effects of bariatric surgery on retinal microvascular health is crucial, as obesity-related changes can lead to serious ocular complications. This study suggests that surgical intervention may improve retinal microvascular parameters, potentially reducing long-term risks.