Utility of 99m Tc-FAPI-46 SPECT/CT in Restaging Hepatocellular Carcinoma : A Case Report.

Clin Nucl MedSep 9, 2026 (epub)
Case ReportOncology (Medical)Nuclear MedicineRadiology (Diagnostic)

Faeze Rabani, Fatemeh Taheri, Ali Emadi Torghabeh et al.

✦ AI-curated · Sources linked

Case in brief

A 54-year-old man with hepatocellular carcinoma developed diffuse bone pain six months after radiofrequency ablation. Restaging with 99mTc-FAPI-46 SPECT/CT showed locally active primary HCC and widespread FAPI-avid bone metastases, establishing extensive extrahepatic disease.

What made this case unusual

The scan demonstrated both locally active HCC and widespread bone metastases, with conspicuous uptake in extrahepatic lesions.

Diagnostic / clinical pearl

In this case, 99mTc-FAPI-46 SPECT/CT visualized active primary HCC and widespread bone metastases during restaging.

Why it matters

The report presents FAPI-46 SPECT/CT as an accessible imaging option for assessing disease extent in HCC, including extrahepatic lesions.

Source

PubMed · PMID 42725471

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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