Caudal versus penile block and urethrocutaneous fistula formation following hypospadias repair in children <2 years: a multicenter randomized clinical trial.

Reg Anesth Pain MedOct 5, 2026 (epub)

Andreas Taenzer, Tessa N Mandler, Alexia Gagliardi et al.

✦ AI-curated · Sources linked

In 30 seconds

This multicenter randomized controlled trial evaluated the incidence of urethrocutaneous fistula (UCF) formation in children under 2 years undergoing hypospadias repair with either caudal or penile block. Among 161 participants, UCF occurred in 8.9% of the caudal block group and 7.3% of the penile block group, showing no significant difference (RR=0.98; p=0.9).

Key findings

  • UCF occurred in 8.9% of the caudal block group and 7.3% of the penile block group.
  • Proximal meatal position increased UCF risk (RR=2.8; p=0.002).
  • Caudal block patients received less intraoperative opioids (33% vs 56%; p<0.001).
  • Caudal block was associated with lower PACU FLACC scores (0.49±1.34 vs 1.14±2.3; p=0.03).

Why it matters

Understanding the impact of anesthesia techniques on postoperative outcomes, such as UCF formation, is crucial for optimizing care in pediatric patients undergoing hypospadias repair. This study provides insights into pain management and complication rates associated with different anesthesia methods.

What to keep in mind

The study faced incomplete enrollment and loss to follow-up, which may affect the reliability of the findings.

Source

Published in Reg Anesth Pain Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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