Multilevel thoracic ossification of the yellow ligament in a Cowden syndrome patient.
Ohsang Kwon, Jaehyuk Choi, Jun Hyeong Ahn et al.
✦ AI-curated · Sources linked
Case in brief
A female in her late 30s with Cowden syndrome presented with extensive thoracic ossification of the yellow ligament, leading to severe spinal cord compression. She underwent a T10-11 posterior decompressive laminectomy and fusion, which successfully restored her ambulatory function and improved motor strength. This case emphasizes the need for awareness of this condition in patients with PTEN-related disorders.
What made this case unusual
The case highlights the development of extensive thoracic ossification of the yellow ligament in a patient with Cowden syndrome, a rare association that warrants further investigation.
Diagnostic / clinical pearl
Clinicians should consider the possibility of ossification of the yellow ligament in patients with PTEN-related disorders who present with neurological symptoms.
Why it matters
This case underscores the importance of spinal surveillance in patients with Cowden syndrome, as they may be at risk for complications like ossification of the yellow ligament.