Primary Hepatic Lymphoma with Hepatocellular Carcinoma: A Case Report.
Yunxi Tang, Yifei Zhan, Xiuying Xu et al.
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Case in brief
A patient with hepatocellular carcinoma (HCC) presented with atypical imaging findings that led to the discovery of primary hepatic lymphoma (PHL). The case highlights the diagnostic challenges in distinguishing between these two conditions. The patient underwent a thorough assessment of the lesions identified through indocyanine green (ICG) imaging, which informed the decision-making process regarding surgical intervention.
Diagnostic / clinical pearl
Clinicians should maintain a high index of suspicion for primary hepatic lymphoma in patients with hepatocellular carcinoma, especially when imaging findings are atypical.
Why it matters
This case emphasizes the need for active screening for PHL in patients with liver lesions, as well as the limitations of ICG imaging for small-volume lesions not intended for resection.