A case report of acute liver failure caused by Gyromitra venenata poisoning and a literature review.
Menghan Tang, Qianqian Zhou, Peipei Zuo et al.
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Case in brief
A patient in Guizhou Province, China, developed illness after eating approximately 500 grams of self-gathered wild mushrooms. After an incubation period of approximately 18 h, severe gastrointestinal symptoms—including haematemesis, melena, and abdominal pain—occurred alongside progressive liver injury. Transaminases were markedly elevated, and coagulation disorders were consistent with acute liver failure and severe gastrointestinal haemorrhage. Retrospective epidemiological investigation and molecular testing identified the suspected mushroom as Gyromitra venenata. UPLC-MS/MS screening for 13 common mushroom toxins was negative.
What made this case unusual
The case documents acute liver failure with severe gastrointestinal haemorrhage following suspected Gyromitra venenata poisoning, highlighting a clinical presentation beyond the neuropsychiatric and haemolytic forms noted by the authors.
Diagnostic / clinical pearl
In suspected wild-mushroom poisoning, acute liver injury with severe gastrointestinal haemorrhage may occur with Gyromitra venenata; species identification may require epidemiological investigation and molecular testing.