Incidence and risk factors for lower-extremity deep vein thrombosis in postoperative patients with spontaneous intracerebral hemorrhage: A systematic review and meta-analysis.
Medicine (Baltimore)Sep 11, 2026
Lingguo Lei, Meijin Li, Meng Li et al.
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In 30 seconds
This systematic review and meta-analysis examined the incidence and risk factors for lower-extremity deep vein thrombosis (DVT) in postoperative patients with spontaneous intracerebral hemorrhage. Involving 3378 patients from 15 studies, the analysis revealed a pooled DVT incidence of 23% (95% CI: 18%-28%). Key risk factors included older age, elevated D-dimer levels, and prolonged bedridden duration.
Key findings
- The pooled incidence of postoperative lower-extremity DVT was 23% (95% CI: 18%-28%).
- Older age was associated with higher odds of DVT (OR = 2.45, 95% CI: 1.76-3.39).
- Prolonged bedridden duration increased DVT odds significantly (OR = 4.30, 95% CI: 2.91-6.37).
- Hypertension was linked to a higher risk of DVT (OR = 3.69, 95% CI: 2.31-5.88).
Why it matters
Understanding the incidence and risk factors for DVT in postoperative patients is crucial for developing effective prevention strategies. This knowledge can help clinicians identify high-risk patients and implement appropriate interventions to reduce DVT occurrence.