Efgartigimod as adjunctive therapy for immunotherapy-dependent autoimmune diencephalitis: A case report.

Medicine (Baltimore)Sep 11, 2026
Case ReportNeurologyOpen access

Chang Li, Xiang Yin, Menghan Jia et al.

✦ AI-curated · Sources linked

Case in brief

A middle-aged male presented with acute symptoms of autoimmune diencephalitis, including headache, fever, seizures, and impaired consciousness, lasting over three months. Diagnosis was confirmed through laboratory tests and MRI. Treatment included glucocorticoids, intravenous immunoglobulin, mycophenolate mofetil, and efgartigimod. The addition of efgartigimod allowed for successful glucocorticoid tapering and led to gradual recovery.

Diagnostic / clinical pearl

Efgartigimod may serve as an effective adjunctive therapy in managing autoimmune diencephalitis, particularly in cases dependent on immunotherapy.

Source

PubMed · PMID 42736765Free full text on PubMed Central

Published in Medicine (Baltimore). This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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