Cost-effectiveness analysis of omeprazole for preventing esophageal stricture in patients with Zargar grade 2b and 3a corrosive esophageal injuries: A trial-based economic evaluation.
Prasit Mahawongkajit, Saritphat Orrapin, Prakitpunthu Tomtitchong et al.
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In 30 seconds
This randomized controlled trial evaluated the cost-effectiveness of omeprazole combined with standard treatment versus standard treatment alone in adults with Zargar grade 2b and 3a corrosive esophageal injuries. The study found that the incidence of esophageal stricture was 20% in the omeprazole group compared to 70% in the standard treatment group, with omeprazole reducing healthcare costs by THB 4642.30 per patient.
Key findings
- The incidence of esophageal stricture was 20% in the omeprazole group versus 70% in the standard treatment group.
- Omeprazole reduced healthcare costs by THB 4642.30 per patient from the provider perspective.
- 68.3% of probabilistic simulations favored omeprazole from the provider perspective.
Why it matters
Understanding the cost-effectiveness of treatments for corrosive esophageal injuries is crucial for optimizing resource allocation and improving patient outcomes. This study suggests that adding omeprazole may reduce both the incidence of strictures and healthcare costs.