Type 2 diabetes mellitus complicated by acquired reactive perforating collagenosis: A case report and literature review.
Li Li, Hanpeng Wu, Liuyan Zhao
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Case in brief
A 66-year-old female with a 22-year history of type 2 diabetes presented with poor blood glucose control and a 3-month history of itching and rash. Examination revealed erythema, papules, and nodules on the lower extremities. Histopathology confirmed acquired reactive perforating collagenosis (ARPC). Treatment with antihistamines, topical corticosteroids, and blood glucose management led to resolution of skin lesions and improved glucose control.
Diagnostic / clinical pearl
Clinicians should consider acquired reactive perforating collagenosis as a potential cutaneous manifestation in patients with poorly controlled diabetes, particularly when skin lesions present or worsen.
Why it matters
This case highlights the importance of addressing systemic conditions like hyperglycemia in managing skin disorders, emphasizing a comprehensive approach to patient care.