Successful treatment of massive stage IIIB cervical cancer with a spindle cell component: A case report.
Hua Jin, Zhengri Piao, Weibo Wen
✦ AI-curated · Sources linked
Case in brief
A 33-year-old woman presented with a massive cervical mass measuring 14 × 13 × 13 cm, accompanied by intermittent vaginal bleeding and progressive fatigue. Biopsy confirmed stage IIIB cervical squamous cell carcinoma with a spindle cell component. The patient underwent neoadjuvant chemotherapy, followed by concurrent chemoradiotherapy and bevacizumab, resulting in complete remission at 6 months with no signs of recurrence or metastasis.
What made this case unusual
The case highlights the successful management of a giant cervical tumor, which is rarely encountered and lacks established treatment protocols.
Diagnostic / clinical pearl
This case underscores the potential of individualized sequential multimodal therapy in achieving complete remission in patients with bulky stage IIIB cervical cancer.
Why it matters
The findings may inform treatment strategies for similarly large cervical tumors, emphasizing the importance of a tailored approach in oncology.