Effects of 12 weeks of resistance and concurrent training with graded protein intakes on lipid profile, kidney and liver biomarkers in middle-aged to older women.
Eur J NutrSep 15, 2026 (epub)
Reza Bagheri, Hamid Ghobadi, Mehdi Kargarfard et al.
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In 30 seconds
This randomized controlled trial investigated the effects of varying protein intakes during resistance training (RT) and concurrent training (CT) on lipid profiles and biomarkers in 108 middle-aged to older women. After 12 weeks, triglycerides, total cholesterol, LDL-C, and apolipoprotein B decreased, while HDL-C increased across all groups. Notably, CT showed more favorable lipid changes compared to RT alone.
Key findings
- Triglycerides, total cholesterol, LDL-C, and apolipoprotein B decreased in all conditions.
- HDL-C increased across all protein intake conditions.
- Urea, blood urea nitrogen, and creatinine levels increased, while eGFR estimates decreased.
- Liver enzymes ALT, AST, and GGT showed significant differences based on protein intake.
Why it matters
Understanding the impact of protein intake and exercise modality on lipid profiles and biomarkers is crucial for optimizing health interventions in middle-aged to older women, particularly regarding cardiovascular and metabolic health.