CanDo (Canadian Donor Milk) randomised controlled trial: pasteurised human donor milk supplementation in the well-baby unit - protocol.

In 30 seconds

The CanDo trial is a randomized controlled trial assessing the effects of pasteurised human donor milk versus formula supplementation in infants at higher risk for supplementation in a well-baby unit. Conducted at Mount Sinai Hospital, Toronto, it aims to determine the impact on exclusive human milk feeding at 4 months of age among 112 infants. The study addresses a significant gap in clinical evidence regarding donor milk use.

Key findings

• The primary outcome is exclusive human milk feeding at 4 months of age.
• Secondary outcomes include any or exclusive human milk feeding at 1, 2, and 3 months.
• The trial includes assessments of infant growth, health indicators, and parental mental health.

Why it matters

This study is crucial as it seeks to provide evidence on the optimal supplementation choice for vulnerable infants, potentially influencing clinical practices and policies in newborn feeding.