Effectiveness of a school-based multicomponent intervention on parental HPV knowledge, vaccination attitudes, and children's HPV vaccine completion: A mixed-methods cluster randomized controlled trial.
Yudisa Diaz Lutfi Sandi, Li-Min Wu, Esti Andarini et al.
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In 30 seconds
This mixed-methods cluster randomized controlled trial evaluated a school-based multicomponent intervention aimed at improving parental HPV knowledge, attitudes, and daughters' vaccination rates in Indonesia. The intervention, which included an educational video and facilitated discussions, resulted in significantly higher HPV knowledge and more positive attitudes among parents, as well as improved vaccine initiation and completion rates in the intervention group compared to controls.
Key findings
- The intervention group had significantly higher HPV knowledge (F(1, 362) = 43.51, p < .001).
- Parental attitudes towards HPV vaccination were more positive in the intervention group (F(1, 362) = 14.38, p < .001).
- Vaccine initiation and completion rates were significantly higher in the intervention group (χ² = 5.40, p = .020).
- Qualitative interviews revealed that the intervention corrected misconceptions and strengthened trust in the vaccination program.
Why it matters
Enhancing parental knowledge and attitudes towards HPV vaccination is crucial for increasing vaccine uptake. This study demonstrates that structured educational interventions can effectively address misconceptions and support informed decision-making, which is essential for public health initiatives.