A cluster-randomized trial of the school-based 'Superprotegidas' behavioral intervention to improve HPV vaccination uptake in Colombian girls.
Veronica Cordoba-Sanchez, Mariantonia Lemos, Ana Milena Gaviria-Gómez et al.
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In 30 seconds
This cluster-randomized trial assessed the 'Superprotegidas' behavioral intervention aimed at increasing HPV vaccination rates among Colombian girls aged 9-14. The study found that post-intervention vaccination rates were significantly higher in the intervention group (52.4%) compared to the control group (28.6%), with an odds ratio of 2.75 (95% CI: 1.06-7.12).
Key findings
- Post-intervention vaccination rates were 52.4% in the intervention group versus 28.6% in the control group.
- The odds ratio for vaccination in the intervention group was 2.75 (95% CI: 1.06-7.12).
- Predictors of vaccination included lower school level and higher behavioral driver scores.
- Higher caregiver self-efficacy was also associated with increased vaccination rates.
Why it matters
Increasing HPV vaccination rates is crucial for preventing cervical cancer. This study demonstrates that school-based behavioral interventions can effectively enhance vaccination uptake among young girls and their caregivers.