Persistent Agmination of Lymphomatoid Papulosis with Features of Lymphomatoid Papulosis in Both the Regressing Papular Component and the Persistent Patch: A Case Report and Review of the Literature.
Ana Spajic, Larisa J Geskin, Cynthia M Magro
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Case in brief
An 18-year-old woman with a history of Type B lymphomatoid papulosis (LYP) presented with a persistent localized patch on her thigh, accompanied by episodic papules. Histological analysis revealed overlapping features of LYP and pityriasis lichenoides chronica, complicating differentiation from early-stage cutaneous T-cell lymphoma. The case highlights the persistence of LYP, which challenges the notion of it being a strictly lymphoproliferative disorder.
Diagnostic / clinical pearl
Clinicians should be aware that persistent lesions in lymphomatoid papulosis can exhibit histological features similar to cutaneous T-cell lymphoma, complicating diagnosis.
Why it matters
This case underscores the need for careful histological evaluation in persistent lymphomatoid papulosis, as it may not always conform to typical lymphoproliferative disorder expectations.