Primary breast diffuse large B-cell lymphoma mimicking breast carcinoma: A case report and literature review.

Medicine (Baltimore)Sep 18, 2026
Case ReportOncology (Medical)Pathology (Anatomic & Clinical)Radiology (Diagnostic)

Longquan Li, Hongxi Yao, Siyu Liu et al.

✦ AI-curated · Sources linked

Case in brief

A 59-year-old postmenopausal woman presented with a painless right breast mass, initially suspected to be breast carcinoma based on imaging studies. Core needle biopsy revealed diffuse infiltration by atypical lymphoid cells, leading to a diagnosis of primary breast diffuse large B-cell lymphoma (PB-DLBCL). The patient underwent R-CHOP chemoimmunotherapy, resulting in complete metabolic resolution of the lesion at follow-up.

Diagnostic / clinical pearl

Primary breast diffuse large B-cell lymphoma can mimic breast carcinoma on imaging, necessitating a tissue diagnosis for accurate identification and treatment planning.

Source

PubMed · PMID 42760664

Published in Medicine (Baltimore). This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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