Collagenous gastritis in pediatric patients: Two case reports and literature review.
Baoqi Chen, Haiyan Liu, Jinming Gong et al.
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Case in brief
Two pediatric cases of collagenous gastritis (CG) are reported. The first case involved a 7-year-old girl with severe iron-deficiency anemia and pallor, where EGD revealed fragile gastric mucosa and histopathology confirmed CG. The second case was a 12-year-old girl with recurrent anemia and fatigue, showing thickened gastric folds on EGD. Both patients received supportive treatment and showed improvement in anemia during follow-up.
Diagnostic / clinical pearl
Histopathological examination revealing subepithelial collagen deposition with positive Masson's trichrome staining is crucial for diagnosing collagenous gastritis in pediatric patients.
Why it matters
Collagenous gastritis should be considered in children with unexplained iron-deficiency anemia, particularly when gastrointestinal symptoms are present, to facilitate timely diagnosis and management.