Nasal NUT carcinoma with repeated responses during multimodal treatment incorporating radiotherapy: A case report.
Qi An, Yuxuan Tao, Peiguo Wang et al.
✦ AI-curated · Sources linked
Case in brief
A 40-year-old woman with nasal NUT carcinoma presented with severe symptoms including orbital pain, visual impairment, and lower-limb paralysis after initial surgery. Pathologic evaluation confirmed the diagnosis. She underwent multimodal treatment, including radiotherapy and systemic therapies, resulting in significant symptom relief and imaging responses. Despite these interventions, she succumbed to the disease approximately 12 months post-surgery.
Diagnostic / clinical pearl
NUT carcinoma can present with aggressive symptoms and may respond to multimodal treatment, including radiotherapy, which can provide palliative benefits.
Why it matters
This case highlights the potential for radiotherapy to play a role in managing rare malignancies like NUT carcinoma, emphasizing the need for individualized treatment approaches.