Olanzapine-Induced Rapid Weight Gain and Metabolic Disorders: A Case Series.
Michal Smogur, Séverine Crettol, Céline Dubath et al.
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Case in brief
This case series highlights four patients who experienced rapid and significant weight gain while on olanzapine, with three developing new-onset metabolic syndrome. The cases illustrate the challenges in managing these adverse effects and the subsequent evolution of their conditions following treatment modifications.
Diagnostic / clinical pearl
Clinicians should be vigilant for rapid weight gain and metabolic syndrome in patients treated with olanzapine, as these complications can arise quickly and require careful management.
Why it matters
Understanding the metabolic risks associated with olanzapine is crucial for optimizing patient care and preventing long-term health issues in psychiatric populations.