Simultaneous Thyroid Eye Disease and IgG4-Related Orbital Disease in a Patient With Diabetes Mellitus: A Case Report.
Brenda Hayatulhaya, Tomoyuki Kashima
✦ AI-curated · Sources linked
Case in brief
A 72-year-old man with a history of thyroid eye disease and diabetes presented with progressive proptosis and orbital swelling. After years of being denied surgery due to high risks, he underwent orbital tumor resection and decompression surgery, which alleviated his symptoms. Histopathological analysis confirmed the presence of IgG4-related orbital disease, necessitating further surgical intervention.
What made this case unusual
The simultaneous occurrence of thyroid eye disease and IgG4-related orbital disease in this patient is particularly rare and presented significant diagnostic challenges.
Diagnostic / clinical pearl
Clinicians should consider the possibility of concurrent inflammatory orbital conditions, such as IgG4-related disease, in patients with atypical presentations of thyroid eye disease.
Why it matters
Recognizing the coexistence of these conditions can influence surgical management strategies and improve patient outcomes in complex cases.