Rapid choroidal neovascularization after non-flap internal limiting membrane peeling for macular hole in a patient with AMD: a case report and literature review.

BMC OphthalmolSep 18, 2026 (epub)
Case ReportOphthalmologyOpen access

Buğra Karasu, Büşra Yılmaz Tuğan, Enes Kesim et al.

✦ AI-curated · Sources linked

Case in brief

A 70-year-old female with age-related macular degeneration (AMD) underwent uncomplicated macular hole surgery involving non-flap internal limiting membrane (ILM) peeling. Six weeks postoperatively, she experienced a sudden decline in visual acuity due to rapid choroidal neovascularization (CNV) at the ILM peeled-off area. The patient was subsequently treated with intravitreal aflibercept.

What made this case unusual

The rapid onset of CNV following non-flap ILM peeling in a patient with AMD is noteworthy, as this complication is typically rare and often associated with different surgical techniques.

Diagnostic / clinical pearl

Clinicians should be aware that choroidal neovascularization can develop rapidly after standard ILM peeling in patients with underlying AMD, necessitating close monitoring post-surgery.

Why it matters

This case underscores the importance of recognizing potential complications in patients with pre-existing conditions, highlighting the need for vigilance in the postoperative management of macular hole surgeries.

Source

Published in BMC Ophthalmol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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